abstract：BACKGROUND:Acute kidney injury (AKI) occurs in 22.4 - 100% of critically-ill hospitalized patients with influenza infection. In up to 2/3, it is severe enough to necessitate renal replacement therapy. We aimed to document the incidence of AKI among patients with influenza-related critical illness and its relation to cl...

journal_title：Clinical nephrology

authors： Dovč A,Premru V,Pečavar B,Ponikvar R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Acute granulomatous interstitial nephritis (AGIN) in native kidneys is most commonly linked to drugs. In allografts, it is a rare complication, and it occurs mostly with infections. CASE PRESENTATION:Our case report presents AGIN with simultaneous acute cellular rejections and acute tubular necrosis in a ki...

journal_title：Clinical nephrology

authors： Avguštin N,Kovač D,Kojc N,Mlinšek G,Lindič J

更新日期：2017-01-01 00:00:00

abstract：:This case report describes a patient with a previous history of autoimmune pancreatitis secondary to IgG4-related disease, who developed an overt nephrotic syndrome due to membranous nephropathy, surprisingly idiopathic. In all the previously described cases with both concurrent diseases, membranous nephropathy was co...

journal_title：Clinical nephrology

authors： Acevedo Ribó M,Ahijado Hormigos FJ,Díaz F,Romero Molina M,Fernandez Rojo MA,Garcia Rubiales MA,García Diaz E

更新日期：2016-12-01 00:00:00

abstract：:We report a case of metformin-associated lactic acidosis (MALA) in a 66-year-old man with end-stage renal disease on peritoneal dialysis (PD). The patient presented with severe lactic acidosis and was treated successfully with automated peritoneal dialysis (APD). During the treatment, PD solution was prepared from hem...

journal_title：Clinical nephrology

authors： Gao J,Gu Z,Xu Y,Na Y

更新日期：2016-11-01 00:00:00

abstract：:Eculizumab, a terminal complement inhibitor, has recently been used successfully to both prevent and treat the recurrence of atypical hemolytic uremic syndrome (aHUS) post renal transplantation. We describe a case that highlights the need to monitor the effects of eculizumab on the complement system and in this case a...

journal_title：Clinical nephrology

authors： Riddell A,Goodship T,Bingham C

更新日期：2016-10-01 00:00:00

abstract：:Rheumatic disease is the dominant cause of amyloid A (AA) amyloidosis, but other chronic inflammatory diseases may have similar consequences. Hidradenitis suppurativa (HS) is a relatively common, but little known skin disease characterized by chronic inflammation. Here we present a case of chronic HS leading to biopsy...

journal_title：Clinical nephrology

authors： Schandorff KD,Miller IM,Krustrup D,Jemec GB,Marckmann P

更新日期：2016-07-01 00:00:00

abstract：AIMS:To investigate the clinicopathologic features of IgA nephropathy (IgAN) patients with different levels of proteinuria and its clinical significance. METHODS:This was a single-center retrospective cohort study. Patients with biopsy-proven primary IgAN were enrolled from January 2006 to December 2011 in The First A...

journal_title：Clinical nephrology

authors： Ai Z,Xu R,Liu W,Zhou Q,Li B,Huang F,Yu X,Yang Q

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Autoimmune polyglandular syndrome type 1 (APS 1) is an autosomal recessive disorder characterized by immune injury of multiple organ systems (primarily endocrine) secondary to a mutation in the autoimmune regulator (AIRE) gene. In some cases, patients develop tubulointerstitial nephritis (TIN) and progress t...

journal_title：Clinical nephrology

authors： Gwertzman R,Corey H,Roberti I

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Increased mortality rate in chronic hemodialysis (HD) patients is partly attributed to a chronic inflammatory state. Neutrophil-lymphocyte ratio (NLR), defined as the neutrophil count divided by lymphocyte count, is increasingly recognized as a marker of systemic inflammation, but its prognostic value in HD ...

journal_title：Clinical nephrology

authors： Ouellet G,Malhotra R,Penne EL,Usvya L,Levin NW,Kotanko P

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Early retraining of patients/caregivers at 3 months after peritoneal dialysis (PD) initiation is recommended to prevent peritonitis. We sought to better understand if the risk of peritonitis was highest early after the initiation of PD and if the risk varied by time on therapy and by organism. METHODS:Using...

journal_title：Clinical nephrology

authors： Perl J,Parpia S,Nessim SJ

更新日期：2016-04-01 00:00:00

abstract：AIMS:Cardiovascular (CV) events are the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD), including those patients on peritoneal dialysis (PD). Fibroblast growth factor 23 (FGF23) has been associated with left ventricular hypertrophy (LVH) and mortality in patients with CKD. Howeve...

journal_title：Clinical nephrology

authors： Sarmento-Dias M,Santos-Araújo C,Poínhos R,Oliveira B,Silva IS,Silva LS,Sousa MJ,Correia F,Pestana M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:To identify the relationship between predialysis pulse wave velocity (PWV), postdialysis PWV during 1 hemodialysis (HD) session, and deaths in maintenance HD patients. METHODS:43 patients were recruited. PWV was measured before and after one HD session and dialysis- related data were recorded. Clinical data...

journal_title：Clinical nephrology

authors： Fu X,Yang J,Fan Z,Chen X,Wu J,Li J,Wu H

更新日期：2016-02-01 00:00:00

abstract：:Fibrillary glomerulonephritis (FGN) is a rare cause of rapidly progressive glomerulonephritis (RPGN). We report a case of FGN in which the patient presented with a clinical pulmonary-renal syndrome and whose kidney biopsy showed > 90% crescents on light microscopy. Immunofluorescence microscopy showed pseudo-linear Ig...

journal_title：Clinical nephrology

authors： Thomas JA,Vasin D,Lin M,Anderson AE,Alpers CE

更新日期：2016-02-01 00:00:00

abstract：:ISN (the International Society of Nephrology) is a global organization with more than 9,000 members in 130 countries. The ISN's mission is to "advance the diagnosis, treatment, and prevention of kidney diseases in the developing and developed world". ISN delivers this mission in low-resource settings through its five ...

journal_title：Clinical nephrology

authors： Feehally J

更新日期：2016-01-01 00:00:00

abstract：AIMS:To delineate the kidney transplantation programs in the Middle East and to provide a comparative summary with other international datasets where deemed appropriate. PATIENTS AND METHODS:Data regarding kidney transplantation as the treatment of choice amongst renal replacement therapies in different countries in t...

journal_title：Clinical nephrology

authors： Rouchi AH,Mahdavi-Mazdeh M

更新日期：2016-01-01 00:00:00

abstract：:An effective workforce is essential for delivery of high-quality chronic disease care. Low-income nations are challenged by a dearth and/or maldistribution of an essential workforce required for all chronic disease care including chronic kidney disease (CKD). Nephrology education and training in developed countries ha...

journal_title：Clinical nephrology

authors： Okel J,Okpechi IG,Qarni B,Olanrewaju T,Courtney MJ,Luyckx V,Naicker S,Bello AK

更新日期：2016-01-01 00:00:00

abstract：:Africa is underdeveloped in terms of treatment options for patients with end-stage renal failure. Economic growth and corresponding increases in health expenditures in the African region mean that we can confidently anticipate increased demand for organ transplantation within the region over the next few years. Renal ...

journal_title：Clinical nephrology

authors： Muller E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Ertapenem is a broad-spectrum and long-acting carbapenem which is predominantly eliminated by the kidneys, and it requires dose adjustment in renal failure. Although it is known that excessive doses of ertapenem can cause neurotoxicity, there are very few case reports of ertapenem-induced reversible peripher...

journal_title：Clinical nephrology

authors： Kara E,Sahin OZ,Ayaz T,Yildirim S,Sahutoglu T,Tufekci A

更新日期：2015-12-01 00:00:00

abstract：AIMS:X-linked Alport syndrome (AS) is a monogenic inherited disorder of type IV collagen, a structural protein in the kidney and cochlea. Males typically exhibit a severe phenotype with end-stage renal disease (ESRD) and/or deafness by early adulthood. Because of the presence of two X chromosomes, females often have a ...

journal_title：Clinical nephrology

authors： Allred SC,Weck KE,Gasim A,Mottl AK

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND/AIMS:Aminoglycosides are a major weapon against serious Gram-negative rod infections, yet aminoglycoside usage is limited by the risk of nephrotoxicity. The risk of toxicity is reduced by extended-interval dosing of aminoglycosides, defined as 5 - 7 mg/kg given intravenously in intervals of 24 hours or great...

journal_title：Clinical nephrology

authors： Chuk AC,Saeed F,Kousar N,Burrill S,Barns B,Rickrode G,Fu J,Katrych O,Saunders-Hao P,Block C,Lahey T

更新日期：2015-10-01 00:00:00

abstract：INTRODUCTION:Calcineurin inhibitors are critical-dose drugs with a narrow therapeutic range and optimal monitoring strategies are discussed in terms of safety and efficacy. A new pharmacodynamic monitoring tool - assessing the expression of nuclear factor of activated T-cells (NFAT)-regulated genes - has been establish...

journal_title：Clinical nephrology

authors： Sommerer C,Zeier M,Meuer S,Giese T

更新日期：2015-09-01 00:00:00

abstract：:Kidney transplantation (KTx) is the treatment of choice for eligible patients suffering from anti-neutrophil cytoplasmic antibody(ANCA)-associated vasculitis (AAV) who are in clinical remission, regardless of ANCA status. With current immunosuppressive protocols, the recurrence rate of this primary disease in the kidn...

journal_title：Clinical nephrology

authors： Le Berre L,Dufay A,Cantarovich D,Meurette A,Audrain M,Giral M,Blancho G,Fakhouri F,Hourmant M,Dantal J

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Calcific uremic arteriolopathy (CUA) is a life-threatening condition almost exclusively affecting patients with end-stage renal failure. Several therapies have been employed to treat this disease with irregular results. METHODS:Comparison of a prospective case series with a historical cohort....

journal_title：Clinical nephrology

authors： Torregrosa JV,Sánchez-Escuredo A,Barros X,Blasco M,Campistol JM

更新日期：2015-04-01 00:00:00

abstract：INTRODUCTION:Excessive relative interdialytic weight gain (RIDWG, %) is an important risk factor for long-term adverse cardiovascular outcomes in chronic hemodialysis (HD) patients. On the other hand, it may also be an index of good appetite and nutritional status. We aimed to assess the relationship between RIDWG and ...

journal_title：Clinical nephrology

authors： Ahbap E,Sakaci T,Kara E,Sahutoglu T,Koc Y,Basturk T,Sevinc M,Akgol C,Kayalar AO,Ucar ZA,Bayraktar F,Unsal A

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:A HIV positive-to-positive program was started in South Africa in 2008. The program was started because dialysis is not freely available to everyone, but severely limited and only available to a selected group of patients. PATIENTS AND METHODS:Between September 2008 and March 2015, 29 patients were transpla...

journal_title：Clinical nephrology

authors： Muller E

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:The history of organ shortage has been approached differently by different countries. This review tries to discuss the inverted funnel approach of Iran. METHODS:The whole history of transplants in the country can be divided in three phases of legally regulated living unrelated kidney donation, legislation...

journal_title：Clinical nephrology

authors： Mahdavi-Mazdeh M,Rouchi AH,Khatami SM

更新日期：2015-01-01 00:00:00

abstract：AIMS:Acute kidney injury (AKI) occurs in up to 40% of patients undergoing cardiac surgery. Proenkephalin A 119-159 (pro-ENK) is a novel, stable surrogate biomarker for enkephalins, endogenous opioids involved in various physiological processes, including neurohormonal stress. MATERIAL AND METHODS:92 patients undergoin...

journal_title：Clinical nephrology

authors： Shah KS,Taub P,Patel M,Rehfeldt M,Struck J,Clopton P,Mehta RL,Maisel AS

更新日期：2015-01-01 00:00:00

abstract：AIM:Accurate assessment and management of hyperphosphatemia is a key component of the care of patients with both acute and chronic kidney disease (CKD). In some cases, hyperphosphatemia may be spurious, and failure to recognize this may lead to complications. We report 6 cases of spurious hyperphosphatemia in patients ...

journal_title：Clinical nephrology

authors： Khan TA,Arif A,Seamonds B,Doyle AM

更新日期：2014-12-01 00:00:00

abstract：:Isolated case reports of peritonitis due to Brucella spp. during peritoneal dialysis (PD) continue to surface in the medical literature. However, the optimal treatment regimen for these patients, in particular with regards to the fate of PD catheter, is still largely unknown. We report a case of brucella peritonitis s...

journal_title：Clinical nephrology

authors： Koz S,Sahin I,Kayabas U,Kuzucu C

更新日期：2014-10-01 00:00:00

abstract：:Co-existence of antineutrophil cytoplasmic antibody (ANCA)-negative pauci-immune crescentic glomerulonephritis (CGN) and thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTPHUS) is extremely rare and has a poor renal prognosis. We report a 76-year-old female that had both ANCA and anti-human lysosomal me...

journal_title：Clinical nephrology

authors： Irifuku T,Naito T,Ogawa T,Masaki T

更新日期：2014-10-01 00:00:00

abstract：:Citalopram is one of the selective serotonin re-uptake inhibitors (SSRIs) most commonly prescribed for depression and many affective disorders. Abrupt cessation of this medication has been associated with dizziness, nausea, myalgias, anxiety and irritability. It is unclear whether blood pressure can be perturbed under...

journal_title：Clinical nephrology

authors： Astorne Figari WJ,Herrmann S,Akogyeram C,Qian Q

更新日期：2014-09-01 00:00:00

abstract：:Acute interstitial nephritis (AIN) is an under recognized and under diagnosed cause of acute kidney injury (AKI). It is estimated to account for 15 - 20% of cases of AKI; it is the reported diagnosis in 2.8% of all kidney biopsies, and 13.5% of biopsies done specifically for acute renal failure. Considerable evidence ...

journal_title：Clinical nephrology

authors： Raghavan R,Eknoyan G

更新日期：2014-09-01 00:00:00

abstract：:Immunoglobulin M (IgM) nephropathy is an idiopathic glomerulonephritis characterized by mesangial deposits of IgM. IgM nephropathy presenting with proteinuria, especially nephrotic syndrome, frequently is steroid-dependent or steroidresistant and associated with reaching endstage renal disease after a 15-year follow-u...

journal_title：Clinical nephrology

authors： Liu S,Zhang D,Zhang Q,Liu W

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To analyze the effect and the time course of continuous veno-venous hemofiltration (CVVH) with net ultrafiltration (UF) on intra-abdominal pressure (IAP) body fluid volumes in septic shock patients with acute kidney injury (AKI). METHODS:Patients were studied at baseline and after 6, 12, 24, 48, 72, and 96 h...

journal_title：Clinical nephrology

authors： Dabrowski W,Kotlinska-Hasiec E,Schneditz D,Zaluska W,Rzecki Z,De Keulenaer B,Malbrain ML

更新日期：2014-07-01 00:00:00

abstract：:Nearly 50% of patients with multiple myeloma develop renal disease; acute kidney injury (AKI) from cast nephropathy, or "myeloma kidney" is the most common type. Development of AKI is associated with worse 1-year survival and reduces the therapeutic options available to patients. Therefore, there is a great need to de...

journal_title：Clinical nephrology

authors： Walther C,Podoll AS,Finkel KW

更新日期：2014-07-01 00:00:00

abstract：:The present report describes a case of nephrotic syndrome (NS) with invasive thymoma. A male patient was hospitalized for severe edema with reduced urine output. He had a history of thymectomy and radiotherapy because of invasive thymoma 4 years before the development of NS. Renal biopsy displayed minimal change disea...

journal_title：Clinical nephrology

authors： Long Q,Wu P,Jiang G,Zhu C

更新日期：2014-04-01 00:00:00

abstract：:Collagenofibrotic glomerulopathy is a very rare glomerular disease characterized by the deposition of Type III collagen fibrils within the subendothelial and mesangial areas, and by elevated serum levels of pro-collagen Type III peptide. We reported here an elderly patient representing the first case of collagenofibro...

journal_title：Clinical nephrology

authors： Fukami K,Yamagishi S,Minezaki T,Nishi S,Hisano S,Okuda S

更新日期：2014-04-01 00:00:00

abstract：:Encapsulating peritoneal sclerosis is a rare condition of a poorly understood pathogenesis with recognized risk factors, such as medications, surgical interventions, systemic diseases, and malignancies. In endstage renal disease it has been associated with chronic peritoneal dialysis. We hereby report the case of a 59...

journal_title：Clinical nephrology

authors： Sonikian M,Pani I,Lazarou D,Khaldi L,Dounavis A,Lafoyanni S,Vlassopoulos D

更新日期：2014-04-01 00:00:00

abstract：:Anti-glomerular basement membrane (anti-GBM) disease is characterized by autoantibodies against antigenic site on type IV collagen of the GBM. The coexistence of anti-GBM disease and other immune complex mediated glomerulonephritis is common. Herein, we describe a patient presented with rapidly progressive glomerulone...

journal_title：Clinical nephrology

authors： Gao B,Li M,Xia W,Wen Y,Qu Z

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Colistin (polymyxin E) was developed ~ 60 years ago but was rarely used in clinical practice during the last 20 years because of concerns related to high rates of nephrotoxicity. However, it was recently reintroduced to clinical practice in many parts of the world for the treatment of multi-drug resistant ...

journal_title：Clinical nephrology

authors： Shavit L,Manilov R,Wiener-Well Y,Algur N,Slotki I

更新日期：2013-12-01 00:00:00